Jonas Salk Papers, 1943 - 1995

Arrangement

Repository
ULS Archives & Special Collections
Title
Jonas Salk Papers
Creator
Salk, Jonas, 1914-1995
Collection Number
UA.90.F89.1
Extent
85.4 Linear Feet
Date
1943-1995
Abstract
The Jonas Salk Papers are centered on the development of the polio vaccine in 1947-1960. Records of local trials are abundant in the form of 50,000 serum cards recording antibody and vaccine data for patients. This collection contains a set of diary notebooks which reveal the challenges of establishing the Salk Institute in 1960-1965 and materials from his lab at the Salk Institute covering his research on cancer, Multiple Sclerosis, and HIV/AIDS (1970s–1980s).
Language
The material in this collection is in English.
Author
Dana Ludgate and Jason M. Rampelt
Publisher
ULS Archives & Special Collections
Address
University of Pittsburgh Library System
Archives & Special Collections
Website: library.pitt.edu/archives-special-collections
Business Number: 412-648-3232 (Thomas) | 412-648-8190 (Hillman)
Contact Us: www.library.pitt.edu/ask-archivist
URL: http://library.pitt.edu/archives-special-collections

Processing Information

This collection was processed by Dana Ludgate and Jason M Rampelt in January-April 2023.

Acquisition Information

Gift of Peter L. Salk, M.D., Darrell J. Salk, M.D., and Jonathan D. Salk, M.D.

Biographical / Historical

Jonas Edward Salk (1914-1995) came to the University of Pittsburgh in 1947 and ran the Virus Research Laboratory (VRL). Max Lauffer, who directed the Virus Research Program at Pitt, brought Salk from the University of Michigan where he had helped Thomas Francis develop a vaccine for influenza. Salk continued his research on influenza in Pittsburgh, but was almost immediately invited by Harry Weaver, Research Director of the National Foundation for Infantile Paralysis (NFIP), to take on the polio typing project. Salk and his team collected samples and identified the three strains of the virus.

Elsie Ward trained in culture techniques and ran the operation which produced virus for the lab from monkey livers. Testing in animals was followed by the earliest safety trials at the D.T. Watson Home (now, Watson Institute, Sewickley, Pennsylvania), the Polk School (now, Polk Center, Polk, Pennsylvania), and several other locations in 1952-1953. By the summer of 1953 it was known that the vaccine, made of a killed virus, was successful in inducing the production of antibodies for all three strains. Salk inoculated himself on May 16, 1953. In March 1954 another trial in local Pittsburgh area schools began, showing the efficacy of the vaccine in naïve participants. This was two months prior to the beginning of the national trial with hundreds of thousands of children participating. The Pittsburgh area schools trials continued through the course of the national trial using the vaccine produced directly by the VRL rather than one produced commercially. More detailed information is provided in Series and Subseries notes.

On April 12, 1955, the success of the national vaccine trial was announced, earning Salk acclaim in newspapers and, later, awards and honors from a wide range of clubs, municipalities, and professional societies. These accolades are well represented in this collection.

After a failed attempt to establish a research institute in Municipal Hospital at the University of Pittsburgh in the late 1950s, Salk left in 1960 to found the Salk Institute in La Jolla, California, a project that was not completed until 1964. He maintained his academic appointment in Pittsburgh until 1963. The transition from Pittsburgh to California was challenging for Salk, which he documented in diaries covering 1960-1965. Salk's own lab in California continued cancer research begun in the VRL. His research continued with proposed therapies for Multiple Sclerosis and HIV/AIDS, the latter resulting in a partnership with a private company.

Jonas Salk was born October 28, 1914, in New York City to Daniel and Dora Salk. He was married to Donna Lindsay in 1939 and divorced in 1968. They had three children, Peter, Darrell, and Jonathan. Jonas Salk remarried Françoise Gilot in 1970. Jonas had a brother, Lee, who died in 1992. Dr Jonas Salk died on June 23, 1995, in La Jolla, California.

Arrangement

I. Personal

II. Personal Correspondence

III. Virus Research Lab, Pittsburgh, Pennsylvania

IV. Salk Institute, La Jolla, California

V. Immune Response Corporation

VI. Lectures and Papers

VII. Photographs

VIII. Newspaper Clippings

IX. Offprints

X. Memorabilia

Scope and Contents

The Jonas Salk Papers cover the period of his development of the polio vaccine in the Virus Research Laboratory (VRL) at the University of Pittsburgh, his transition to the Salk Institute (SI) in La Jolla, California, and some of his research conducted there. The collection also has numerous newspaper clippings about his achievements and several controversies, such as his departure from Pittsburgh and debate about the quality of his vaccine. Memorabilia includes paper certificates and plaques given as honors and awards.

Some documents were found with discernible order, such as long segments of research data cards (Series III), research data graphs (Series IV), and Personal Correspondence (Series II). However, across segments of research data cards, it was necessary to bring them together in chronological groups. Cards had been removed from specialized file drawers, but their placement in drawers sometimes appears to have been in the interests of space rather than order.

File folder titles are rendered in quotation marks when they have been transcribed verbatim. All other folder titles are interpolated with descriptive names. The exception to this use of quotations is Series VI, Lectures and Papers, where quotations simply indicate the title of the lecture or paper.

Preferred Citation

Jonas Salk Papers, 1943-1995, UA.90.F89.1, University Archives, Archives & Special Collections, University of Pittsburgh Library System.

Copyright

The University of Pittsburgh holds the property rights to the material in this collection, but the copyright may still be held by the original creator/author. Researchers are therefore advised to follow the regulations set forth in the U.S. Copyright Code when publishing, quoting, or reproducing material from this collection without the consent of the creator/author or that go beyond what is allowed by fair use.

Access Restrictions

Documents throughout this collection contain patient medical records with Level 2 Protected Health Information (PHI) as defined in the University of Pittsburgh Library System's Policy on Access to Personal Medical and Health Information in Collections and are restricted. Please contact Archives & Special Collections for permission to consult these records.

Related Materials

Jonas Salk Papers, 1921-1991. MSS 1, University of California, San Diego (UCSD).

The collection of Jonas Salk Papers in Pittsburgh complements those in California at UCSD. Patient records in the form of serum cards from the polio vaccine trials in the Pittsburgh collection augment other types of research data in the relevant series in the UCSD collection on polio. The Salk manuscript "Diaries" in Pittsburgh overlap with the UCSD Series "Daily Notes" for 1960-1965. Research files on cancer, M.S., and HIV/AIDS in Pittsburgh add to similar research files in the UCSD collection. For research on influenza, the Pittsburgh collection adds information on Salk's work on military personnel, represented in patient data cards.

Jonas Salk Polio Vaccine Collection, 1917-2005, UA.90.F89, University Archives, Archives & Special Collections, University of Pittsburgh Library System.

Max A. Lauffer Papers, 1915-2013, UA.90.F99, University Archives, Archives & Special Collections, University of Pittsburgh Library System.

Chancellor of the University of Pittsburgh, Edward H. Litchfield, Administrative Files, 1956-1965, UA.2.10.1956-1965, University Archives, Archives & Special Collections, University of Pittsburgh Library System.

Subjects

    Corporate Names

    • University of Pittsburgh. Virus Research Laboratory
    • Salk Institute for Biological Studies

    Personal Names

    • Salk, Jonas, 1914-1995

    Genres

    • Administrative records
    • Research notes
    • Correspondence
    • Papers (documents)
    • Diaries

    Other Subjects

    • Virus diseases -- Research
    • Polio -- Research
    • Influenza -- Research
    • Multiple sclerosis -- Research
    • HIV (Viruses) -- Research
    • Cancer -- Research
    • Polio vaccine -- Research
    • Clinical trials

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